Perturbation of Mouse Glioma Mrs Pattern in Vivo at 7.0 Tesla by Induced Acute Hyperglycemia
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چکیده
INTRODUCTION: H MRS is evolving into an invaluable tool for tumor classification in human patients based on pattern recognition analysis [1] but there is still room for improvement. Here we propose a new approach in this direction: to challenge tumor metabolism in vivo by a defined perturbation and monitor MR spectral pattern changes. PURPOSE: To monitor tumor H MRS pattern changes in mice bearing a stereotactically induced brain glioma during a period of induced acute hyperglycemia.
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تاریخ انتشار 2007